The brain produces certain chemicals (neurotransmitters) that play a role in cognitive function (learning, memory, decision-making, attention), balancing anxiety, stress, mood, sleep-wake cycles, and our overall emotional well-being. When these “feel-good” chemicals are low, it’s harder to think more clearly, remember things, stay focused, and feel calm, joyful, and fulfilled.
Stress and anxiety adversely affect cognitive function by disrupting executive functions of the brain’s prefrontal cortex, impairing memory, decision-making, and sustained attention.
Some existing prescription treatments for anxiety, attention deficits, and cognitive impairment can have unpleasant side effects and are habit-forming. This is why there is a real need for novel, safe, and natural alternatives and treatments to be developed in this field. Science has shown that herbal extracts and phytonutrients like ashwagandha, bacopa monnieri, L-theanine, saffron,lemon balm, and ginkgo are all considered promising non-habit forming, effective, and safer alternatives to prescription synthetic medicines.
That’s why we at OneChoice have crafted a unique formula combining all these natural ingredients in full effective doses to improve cognitive function, reduce stress, tension, and anxiety, and promote emotional well-being.*
Ashwagandha (Withania somnifera) is an adaptogen herb. Adaptogens mimic the body's stress-reducing hormones and increase the body's ability to recover from stress while creating an overall feeling of balance and normalization.
Ashwagandha works to counteract the negative effects of stress on the body by reducing cortisol levels, the "stress hormone." This reduces the negative effects of high (or low levels) of this hormone. This is highly significant as ongoing stress can harm mental and physical health.
Ashwagandha also enhances GABA receptors and regulates serotonin in the brain. It works on neuron receptors, enabling GABA to connect easier. This inhibits the signals present under a stress response in the brain leading to reduced anxiety and improved cognitive function.
L-theanine is a nondietary amino acid that occurs naturally in tea and is the key component of green tea that imparts a sense of relaxation. It's been revered for its ability to boost brain function and promote a relaxed yet alert state of mind for centuries.
Chemically, L-theanine is a derivative of glutamic acid, a significant neurotransmitter in the brain. After consumption, L-theanine can cross the blood-brain barrier and affect brain activity by promoting increased alpha waves and a decrease in beta-brain waves, a pattern of brain activity associated with a more relaxed state without drowsiness. L-theanine also has cognitive-enhancing effects as it can improve alertness, executive function, and memory and enhance sleep quality by promoting a more relaxed state in the brain.
L-theanine has also been shown to suppress the blood pressure-increasing effects of caffeine and may also counteract blood pressure increases under stressful conditions.
Ginkgo biloba (or just ginkgo) is one of the oldest species of trees on earth. Scientists consider it a "living fossil" dating back 270 million years. It has continued to survive even after major extinction events.
Its leaves contain various potentially bioactive compounds, including several flavonoids and terpenoids.
Ginkgo enhances cognitive function by improving blood flow to the brain, reducing oxidative stress, and inhibiting the neurotoxic effects of amyloid beta protein deposits in neural cells.
Saffron is the dried stigma of the Crocus sativus plant native to the Middle East that is known as the world's most expensive culinary spice largely due to how it must be grown and harvested (by hand). Saffron has been used for thousands of years as an anxiolytic, sedative, and antidepressant.
Crocin and safranal are two main ingredients from saffron that can inhibit the uptake of dopamine and norepinephrine in the brain, which helps improve mood.
These compounds can scavenge free radicals, which reduces inflammation, preventing apoptosis and protecting brain cells and mitochondria.
Saffron also inhibits the deposit of amyloid-β, which is associated with the progression of Alzheimer's disease, and the breakdown of acetylcholine (acetylcholinesterase) just like the current medication (donepezil) approved to treat Alzheimer's.
Lemon balm (Melissa officinalis) has been known for centuries for its calming and "antistress" action, promoting sleep and relaxation.
Rosmarinic acid, a compound found in lemon balm, inhibits the GABA transaminase enzyme, which helps maintain adequate levels of GABA in the brain resulting in a calming effect.
Overall, lemon balm increases calmness, memory, and alertness in adults under mental stress. It also contains potent antioxidants protecting brain cells from free radical damage.
Rhodiola rosea is one of the most powerful adaptogens found in nature with a tradition of use to promote well-being that dates back centuries. It was prized for its medicinal properties by the Ancient Greeks and used by the Vikings to enhance strength and endurance.
Rhodiola can increase neuropeptide Y (NPY) levels in the brain, which can enhance mood and cognition. In addition, Rhodiola has been shown to increase beneficial brain mood-boosting chemicals like serotonin, BDNF, oxytocin, and GABA, among others.
Bacopa monnieri, commonly known as Brahmi and water hyssop, is a herb often used in Ayurveda. It is taken to improve cognitive function, stress relief, and general enhancement of vitality.
Bacopa monnieri interacts with the acetylcholine, dopamine, and serotonin systems, but its main mechanism concerns promoting neuron communication. It does this by increasing the growth of dendrites. Bacopa monnieri also has antioxidant effects. Many of these effects come from phytochemicals and active compounds found in bacopa, including triterpenoid saponins and their bacosides.
Research on the potential mechanisms of Bacopa has found promising cognitive effects, including neuroprotection, cognitive enhancement, memory enhancement, and protection against neurodegeneration.
| Serving Size 2 Capsule Servings Per Container 30 |
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| Amount Per Serving | %DV | ||||||||||||||||||||||||
| Ashwagandha Extract (Withania somnifera) (Root) (min. 10% withanolides) | 500 mg | † | |||||||||||||||||||||||
| Bacopa Monnieri Extract (Bacopa monnieri) (Leaf) (min. 45% bacosides) | 250 mg | † | |||||||||||||||||||||||
| Rhodiola Rosea Extract (Rhodiola rosea) (Root) (min. 3% rosavins and 1% salidroside) |
200 mg | † | |||||||||||||||||||||||
| Ginkgo Biloba Extract (Ginkgo biloba) (Leaf) (min. 24% flavonol glycosides and 6% terpene lactones) |
60 mg | † | |||||||||||||||||||||||
| Lemon Balm Extract (Melissa officinalis) (Leaf) (min. 17% hydroxycinnamic acids) |
35 mg | † | |||||||||||||||||||||||
| Saffron Extract (Crocus sativus) (Flower) (min. 3% crocins and 2% safranal) |
30 mg | † | |||||||||||||||||||||||
| L-Theanine | 100 mg | † | |||||||||||||||||||||||
| † Daily Value (DIV) not established |
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